evaluation of antimicrobial resistance of acinetobacter baumannii to imipenem, ciporofloxacin and ceftazidime using e test

background: resistance patterns among nosocomial bacterial pathogens in hospitals may vary widely from country to coun­try at any given point and within the same country over time. acinetobacter baumannii is one of the most important bacte­rium causes hospital acquired infections. therefore, surveillance of antibiotic resistance of a. baumannii is necessary, espe­cially in our country which there is no have much data in this field. methods: in a prospective study, strain comprised of a total of 191 recent clinical isolates selected consecutively from clini­cal infections of separate patients from three university hospitals in tehran. minimum inhibitory concentration (mic) of these organisms for imipenem, ciprofloxacin and ceftazidime was determined using e test method according to clsi guide­line. also, mic 50 and mic 90 percent was calculated for each of these antibiotics. results: the percentages of acinetobacter baumannii isolates susceptible to ciprofloxacin and ceftazidime by e test were 55.5% and 44.5%, respectively. the percentage of bacterium susceptible to imipenem by e test was 72.8%. mic 50 and mic 90 of imipenem in e test were 1.5 and >32, respectively. conclusion: high antimicrobial resistance against a. baumannii species has been seen in iran; therefore, it is necessary to imple­ment some approaches for prevention of bacterial spread.